|
Assay
|
Model system
|
Disease area
|
Sample
quantity required
|
Tentative time required for assay
|
Running cost (Rs/
Sample)*
|
Scientist Involved*
|
Plasmodium falciparum
SYBR Green based assay
|
In- vitro: whole cell assay
|
Malaria |
10 mg
|
1 month |
5000/- |
Dr. Renu Tripathi,
Dr. Niti Kumar |
|
Plasmodium berghei GFP based assay |
In vitro hepatocyte development assay |
Malaria
|
50 mg |
3 month |
12,000/- |
Dr. Satish Mishra |
|
Plasmodium yoelii ( N-67) - Swiss mice
|
In-vivo: Primary model for tissue Schizontocidal assay
|
Malaria |
100 mg |
3 month |
20,000/- |
Dr. Renu Tripathi,
Dr. Satish Mishra |
|
Plasmodium berghei C57BL/6 mice
|
In-vivo malaria liver stage development inhibition assay
|
Malaria |
200 mg |
3 month |
30,000/- |
Dr. Satish Mishra |
|
Plasmodium yoelii ( N-67))/ Plasmodium yoelii MDR/Swiss mice
|
In-vivo blood Schizontocidal assay
|
Malaria |
100 mg |
2 month |
20,000/- |
Dr. Renu Tripathi,
Dr. Satish Mishra |
|
Plasmodium cynomolgi - Rhesus monkey
|
In-vivo: Secondary model for blood Schizontocidal /
Anti-relapse assay
|
Malaria
|
2 gm |
6 month |
50,000/- |
Dr. Renu Tripathi,
Dr. Satish Mishra |
|
Leishmania donovani -Macrophase- Amastigote Luciferase based assay |
In vitro: whole cell assay |
Leishmaniasis |
3.0 gm |
1 month |
Through collaboration |
|
|
Leishmania donovani- Macrophase- Amastigote GFP based assay
|
In vitro: whole cell assay
|
Leishmaniasis
|
15 mg
|
1 month |
5000/- |
Dr. Neena Goyal,
Dr. S. Kar |
|
Leishmania donovani Golden hamster chronic model
|
In vivo: assay
|
Leishmaniasis
|
300 mg
|
2 months |
30,000/- |
Dr. Neena Goyal,
Dr. S. Kar |
|
Brugia malayi- MTT and motility assay
|
In vitro: whole parasite assay
|
Filariasis
|
10 mg |
1 month |
5000/- |
Dr. Mrigank Srivatava |
| Brugia malayi- Adult transplanted in JIRD
|
In vivo: Primary assay
|
Filariasis
|
150 mg |
2 months |
12,000/- |
Dr. Mrigank Srivastava |
|
L3 induced Brugia malayi- Mastomys
|
In vivo: Secondary model
|
Filariasis
|
250 mg |
9 months |
20,000/- |
Dr. Mrigank Srivastava |
* Minimum Quantity of the compound required, running cost of the assay and time required for the assay shall be communicated on request