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Laboratory Animal Division

National Laboratory Animal Center (NLAC) of the CSIR-Central Drug Research Institute, Lucknow being one of the most important technical support infrastructure facilities of the institute is engaged in breeding and providing experimental animals for institute R&D programmes. Besides, NLAC also serves as a national resource of healthy animal to other bonafide governmental and public/private institutions within the acts and provisions of the CPCSEA (Committee for the Purpose of Control and Supervision of Experiments on Animals), Ministry of Environment, Forest and Climate Change, Govt. of India. Historically, the pioneering initiatives of Dr B. Mukerji, then Director of Central Drug Research Institute, and constructive efforts of Dr Jivraj N. Mehta, Chairman, Drugs Sub-Committee of the Board of Scientific and Industrial Research, Govt. of India led to the establishment of animal house facility at CDRI in its Chattar Manzil palace complex which was formally declared open by Prof. Arthur Stoll of Switzerland on January 12, 1952. With advancements in science, the facility has been gradually expanded and modernized. Currently, it houses approximately 25 thousand research animals of more than 8 species and more than 25 inbred & out bred strains and is unique in terms of having disease specific specialized research animal models of mice (inbred strains: Balb/C DBA/J1, db/db, C57BL/6 , AKR, NZB, A/J C3H/Hej, Apoe, NOD etc; out bred strains: Swiss and PS; transgenic strains: APOE, NOS-1, NOS-2, NCF-1, MK2, Le Pr (db); inbred rats: SHR, Wistar; out bred rats: SD, SDnin , DR,CF; out bred and inbred strains of Golden Syrian hamsters, out bred strains of Mastomys coucha, gerbil, English Strain of G.Pig, New Zealand White and Belgian rabbits, sheep and rhesus monkeys.

Major activities/objectives of NLAC

Breeding, production and supply of healthy and defined animals for IAEC approved biomedical research programmes of the institute and other institutions.
Animal health monitoring and quality control through microbiological, pathological, parasitological and radiological screening of animals.
Human resource development programmes through conducting training course and organizing Symposium/Workshop/Seminar in the area of laboratory animal science
Publication and distribution of scientific literature/ newsletter on contemporary issues of lab animals
Generation of substantial revenue through animal sales and supplies
Acting as Referral Center for Scientific and Technical advisory on development of research animals