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Malleswara Rao Kuram, Ph.D.

Sr Scientist,Division Of Medicinal and Process Chemistry

Development of New Reactions Using C-H Bond Functionalization

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Research Interests

Our research group focuses on the development of new synthetic strategies for the synthesis of privileged heterocycles and the application of such to the synthesis bio(active)molecules and in drug discovery.

Transition-Metal-Catalyzed Organic Transformations:
Development of Natural Product Inspired Potential Leads for Bioactive Small Molecules:

Education

Ph.D at School of Chemistry, University of Hyderabad (UoH), Hyderabad in Supervision of Prof. Akhil Kumar Sahoo (01/2008 – 08/2013)
M.Sc Chemical Sciences from Department of Chemistry, Pondicherry University, Puducherry

Ph.D at School of Chemistry, University of Hyderabad (UoH), Hyderabad in Supervision of Prof. Akhil Kumar Sahoo (01/2008 – 08/2013)

M.Sc Chemical Sciences from Department of Chemistry, Pondicherry University, Puducherry

Postdoc

Post-Doctoral fellow at School of Energy and Chemical Engineering, Ulsan National Institute of Science and Technology (UNIST), IBS-CGI, South Korea (with Prof. Sung You Hong; 2015 – 2017)
Post-Doctoral fellow at Division of Chemistry and Biological Chemistry, Nanyang Technological University (NTU), Singapore (with Prof. Naohiko Yoshikai; 2014)

Post-Doctoral fellow at School of Energy and Chemical Engineering, Ulsan National Institute of Science and Technology (UNIST), IBS-CGI, South Korea (with Prof. Sung You Hong; 2015 – 2017)

Post-Doctoral fellow at Division of Chemistry and Biological Chemistry, Nanyang Technological University (NTU), Singapore (with Prof. Naohiko Yoshikai; 2014)

Positions

Scientist at CSIR-Central Drug Research Institute, Lucknow (since 12/2017)

Scientist at CSIR-Central Drug Research Institute, Lucknow (since 12/2017)

Contact Details

Email id: malleswara.kuram[AT]cdri.res.in

Tel: 0522-2772452 EPABX-4673

Selected Publications

1) Copper-Catalyzed Direct Synthesis of 1, 2, 4-Oxadiazoles from Amides and Organic Nitriles by Oxidative N–O Bond Formation M. R. Kuram, W. G. Kim, K. Myung, S. Y. Hong Eur. J. Org. Chem 2016 (3), 438-442

2) A palladium and gold catalytic system enables direct access to O-and S-linked non-natural glyco-conjugates M. H. Jeon, B. P. Mathew, M. R. Kuram, K. Myung, S. Y. Hong. Org. Biomol. Chem. 2016, 14, 11518-11524

3) Direct Access to Benzo [b] furans through Palladium-Catalyzed Oxidative Annulation of Phenols and Unactivated Internal Alkynes M. R. Kuram, M. Bhanuchandra, A. K. Sahoo. Angew. Chem. Int. Ed. 2013, 52, 4607-4612

4) Ru(II)-Catalyzed Intermolecular ortho-C–H Amidation of Aromatic Ketones with Sulfonyl Azides. M. Bhanuchandra, M. R. Yadav, R. K. Rit, M. R. Kuram, A. K. Sahoo Chem. Commun. 2013, 49, 5225-5227

5) Silver (I)-Catalyzed Reaction between Pyrazole and Propargyl Acetates: Stereoselective Synthesis of the Scorpionate Ligands (E)-Allyl-gem-dipyrazoles (ADPs) M Bhanuchandra, M. R. Kuram, A. K. Sahoo J. Org. Chem. 2013, 78, 11824-11834

Awards & Fellowships

Research Group

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