Gopal Gupta, Ph.D.
Senior Principal Scientist, Endocrinology
Novel Targets for Contraception and Reproductive Health
I am the Divisional Chairperson and a Senior Principal Scientist at the Endocrinology Division of CSIR-Central Drug Research Institute, Lucknow, India. In my research, I search for novel targets for contraception and reproductive health. In particular, I am interested in the molecular mechanisms associated with sperm motility initiation during ejaculation, thermal regulation of testicular spermatogenesis, the genetic basis of male infertility and the identification of some common targets on sperm and STD pathogens for designed chemical attack. Furthermore, I study the conceptualized planning, synthesis and evaluation of original chemical entities with sperm immobilizing and anti-STD activities. I have also researched the molecular basis for the development of benign prostatic hyperplasia and prostate cancer.
The basic aims of my research are:
To generate state-of-the-art knowledge in the areas of male reproductive health including spermatogenesis, sperm motility initiation, male-infertility, common STDs and prostatic diseases through fundamental research
To apply this knowledge in the development of novel methods for diagnosis/treatment of male reproductive disorders including infertility and for contraception